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from an anterior to a posterior orientation, with theflaps everted through the introitus (Figure 17-13). Methemoglobinemia is blood locked in an oxidized state that cannotpick up oxygen.
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This view has changed in recent yearsand rare diseases have received much more attention at the scienti?c, political, andsocietal level. Antigenprocessing begins when the APC endocytoses the antigen andbreaks it down into 18 to 20 amino acid peptides. There is a strong empirical drive to randomly assign subjects to untreated controlgroups when testing for treatment effectiveness.
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